Following the success of 2008′s telethon, Stand Up To Cancer will once again be taking over the airwaves to raise money for cancer research, on Friday, September 10th. The telethon will air live and commercial-free on ABC, CBS, FOX, NBC, Bio, Discovery Health, E!, G4, HBO, HBO Latino, MLB Network, mun2, Showtime, Smithsonian Channel, The Style Network, TV One, and VH1.

Executive produced by Laura Ziskin, the special will be hosted Katie Couric, Diane Sawyer, and Brian Williams (the anchors, respectively, of the CBS, ABC and NBC evening news programs), and will feature numerous celebrity cancer survivors who exemplify that cancer can affect even the smartest, strongest and toughest people in our lives. Those expected to participate include Christina Applegate, Lance Armstrong, Fran Drescher, Elizabeth Edwards, Delta Goodrem, Michael C. Hall, Kareem Abdul-Jabbar, Sharon Osbourne, Robin Roberts, Maura Tierney, Sofia Vergara, Marissa Jaret Winokur and Ethan Zohn. The broadcast will be dedicated to the 12 million U.S. cancer survivors and illustrate how groundbreaking research can change the tide in the fight against the disease. Updates will be provided on the work of the five Stand Up To Cancer Dream Teams, and Dr. Sanjay Gupta, CNN’s Chief Medical Correspondent, will report on other new developments. One of the musical performances will be an all-star collaboration led by Stevie Wonder with Natasha Bedingfield, Queen Latifah, Martina McBride, Aaron Neville, and Dave Stewart.

See the press release for more information. Other celebrity participants confirmed for the broadcast include Neil Patrick Harris, Alyson Hannigan, David Boreanaz, Zachary Levi, Lea Michele, Sofia Vergara and many more. To donate visit su2c.org/donate. You can donate any time, you don’t have to wait for the night of the show to help.